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doctor and patient

Treatment Strategies After Denosumab Discontinuation in Non-Metastatic Breast Cancer Treated with AI

Aromatase inhibitors (AIs) are a cornerstone of adjuvant therapy for hormone receptor–positive breast cancer, significantly reducing recurrence and mortality. However, by suppressing estrogen production, AIs accelerate bone loss and increase ...

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February 10, 2026
Figure 1

First Global Consensus on Managing Vertebral Fractures in Advanced Chronic Kidney Disease

A coalition of leading international experts in nephrology, bone health, and musculoskeletal disease has released the first comprehensive Consensus Statement on the Management of Vertebral Fractures in Chronic Kidney Disease ...

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January 22, 2026
vitamin D testing

A practical tool to support harmonization and quality improvement in vitamin D testing

Accurate laboratory results are essential for clinical decisions — but every measurement carries some uncertainty. 

Addressing this challenge, the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)–International Osteoporosis Foundation ...

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September 11, 2025
global barriers and solutions position paper

Closing the care gap: IOF position paper identifies barriers and solutions to global undertreatment of osteoporosis

The International Osteoporosis Foundation (IOF) has issued a landmark Position Paper identifying critical global barriers to osteoporosis care and calling for urgent change to improve access to effective fracture prevention ...

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September 09, 2025
exercise at all ages

New research highlights critical role of movement in lifelong bone health

A new review by the International Osteoporosis Foundation (IOF) Rehabilitation Working Group underscores the powerful impact of lifestyle behaviours—specifically physical activity and sedentary behaviour —on bone health across the human ...

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September 08, 2025
AIBL

New guidance on the management of aromatase inhibitor-associated bone loss in women with hormone-sensitive breast cancer

An updated joint position statement on the management of aromatase inhibitor-associated bone loss (AIBL) addresses the heightened fracture risk in women undergoing endocrine therapy for estrogen-responsive breast cancer, providing practical ...

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August 18, 2025
Bone effects of anti-cancer treatments

New review highlights bone health risks linked to modern cancer treatments

 

The International Osteoporosis Foundation (IOF) Bone and Cancer Working Group has released a comprehensive review detailing the often underrecognized impact of modern anti-cancer treatments on bone health. Published in ...

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June 19, 2025
Bone Microstructure and TBS in Diabetes

New review highlights impact of diabetes on bone health and fracture risk

A landmark narrative review published by the Bone and Diabetes Working Group of the  International Osteoporosis Foundation (IOF) Committee of Scientific Advisors reveals critical insights into how diabetes mellitus alters ...

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June 18, 2025
webinar BTMs

Webinar on the role of bone turnover markers in osteoporosis diagnosis & management

IOF invites to its BoneCast webinar of July 3, 2025, focused on the role of bone turnover markers in osteoporosis diagnosis and management.

Bone turnover markers (BTMs) have become essential ...

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June 12, 2025
Update on the Role of Bone Turnover Markers in the Diagnosis and Management of Osteoporosis

Joint consensus highlights the role of bone turnover markers in osteoporosis diagnosis and management

A new consensus paper, published by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), the International Osteoporosis Foundation (IOF), and the International Federation ...

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March 31, 2025
doctor discussing with patient

Pilot study highlights critical gaps in patients’ osteoporosis awareness and management

Although osteoporosis and related fractures impose a significant and growing burden, the management of this disease, even following fractures, is on the decline. A new groundbreaking pilot study carried out ...

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January 21, 2025

Standardized Nomenclature for Bone Status Indices to Enhance Diagnostic Consistency and Clarity

The Joint International Osteoporosis Foundation (IOF) Working Group and the International Federation of Clinical Chemistry (IFCC) Committee on Bone Metabolism have published important updated guidelines for the correct use of ...

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January 10, 2025

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