A new special issue of Calcified Tissue International & Musculoskeletal Research presents a series of critical reviews and original work that embodies the current state of the art related to our understanding of the pathogenesis, clinical implications, and potential targets of therapeutic interventions for sarcopenia.

In his editorial, special issue editor Professor Roger A. Fielding, states, “Since the original definition of sarcopenia as the age-associated decline in muscle mass, the research community has struggled with the application of appropriate methodologies to precisely and accurately measure muscle mass in humans. The topics in this special issue highlight the remarkable progress that has been made to date on the evaluation, management and development of therapeutic interventions.”

We invite you to read and share the following special issue papers:

• Editorial by Fielding, R.A. (2024) Sarcopenia: An Emerging Syndrome of Advancing Age. Calcif Tissue Int.  https://doi.org/10.1007/s00223-023-01175-z 
  Read only: https://rdcu.be/dvwwL 
• Evans WJ, Cawthon PM (2023) D(3)creatine dilution as a direct, non-invasive and accurate measurement of muscle mass for aging research. Calcified Tissue Int. https://doi.org/10.1007/s00223-023-01124-w
• Wages NP, Mousa MH, Clark LA, Tavoian D, Arnold WD, Elbasiouny SM, Clark BC (2023) Reductions in motor unit firing are associated with clinically meaningful leg extensor weakness in older adults. Calcified Tissue Int.  https://doi.org/10.1007/s00223-023-01123-x
• Thornton M, Sim M, Kennedy MA, Blodgett K, Joseph R, Pojednic R (2023) Nutrition interventions on muscle-related components of sarcopenia in females: a systematic review of randomized controlled trials. Calcified Tissue Int. https://doi.org/10.1007/s00223-023-01157-1
• Faitg J, D’Amico D, Rinsch C, Singh A (2023) Mitophagy activation by urolithin a to target muscle aging. Calcified Tissue Int. https://doi.org/10.1007/s00223-023-01145-5
• Wood BS, Batchek DJ, Lynch DH, Spangler HB, Gross DC, Petersen CL, Batsis JA (2023) Impact of EASO/ESPEN-defined sarcopenic obesity following a technology-based weight loss intervention. Calcified Tissue Int. https://doi.org/10.1007/s00223-023-01138-4 
  Read only:  https://rdcu.be/dvwxt
• Alhmly HF, Fielding RA (2023) A critical review of current worldwide definitions of sarcopenia. Calcified Tissue Int. https://doi.org/10.1007/s00223-023-01163-3  
  Read only: https://rdcu.be/dvwyd  

Journal Editors-in-Chief, Professors René Rizzoli and Stuart Ralston state, “We thank Roger Fielding, Calcified Tissue International’s musculoskeletal research editor, for compiling this special issue with its innovative original research and important reviews. We are confident that readers working in the sarcopenia and muscle field will find this to be a ‘must-read’ issue.”

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About Calcified Tissue International & Musculoskeletal Research
Calcified Tissue International & Musculoskeletal Research is a peer-reviewed journal which publishes original preclinical, translational and clinical research, and reviews concerning the structure and function of bone, and other musculoskeletal tissues in living organisms, as well as clinical studies of musculoskeletal disease. It includes studies of cell biology, molecular biology, intracellular signalling, and physiology, as well as research into the hormones, cytokines and other mediators that influence the musculoskeletal system. The journal also publishes clinical studies of relevance to bone disease, mineral metabolism, muscle function, and musculoskeletal interactions.
2022 Impact Factor: 4.2, 5-Year Impact Factor: 4.1
https://www.springer.com/journal/223 

Editors in Chief: Stuart Ralston and René Rizzoli; Musculoskeletal Research Section Editor: Roger Fielding

About IOF
The International Osteoporosis Foundation (IOF) is the world's largest nongovernmental organization dedicated to the prevention, diagnosis and treatment of osteoporosis and related musculoskeletal diseases. IOF members, including committees of scientific researchers as well as more than 330 patient, medical and research organizations, work together to make fracture prevention and healthy mobility a worldwide heath care priority. https://www.osteoporosis.foundation @iofbonehealth