Austria

• In 2010 approximately 86,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 460,000; economic burden of new and prior fractures € 799 million (in 2010); by 2025 burden will increase by 28 % to € 1,025 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Belgium

• In 2010 approximately 80,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 600,000; economic burden of new and prior fractures € 606 million (in 2010); by 2025 burden will increase by 21 % to € 733 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Bulgaria

• In 2010 approximately 38,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 420,000; economic burden of new and prior fractures € 42 million (in 2010); by 2025 burden will increase by 5 % to € 45 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Cyprus

• In 2010 approximately 5,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 40,000; economic burden of new and prior fractures € 52 million (in 2010); by 2025 burden will increase by 47 % to € 76 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Czech Republic

• In 2010 approximately 72,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 530,000; economic burden of new and prior fractures € 273 million (in 2010); by 2025 burden will increase by 29 % to € 352 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Denmark

• In 2010 approximately 66,000 new fragility fractures; number of people aged 50+ with osteoporosis, approximately 280,000; economic burden of new and prior fractures € 1,055 million (in 2010); by 2025 burden will increase by 27 % to € 1,344 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  . 

• The first hip fracture incidence rate increased by 56% during the period 1987-1997, with an increase of 41% among women and 104% among men aged 50 years and older [5]Giversen, I.M., Time trends of age-adjusted incidence rates of first hip fractures: a register-based study among older people in Viborg County, Denmark, 1987-1997. Osteoporos Int, 2006. 17(4): p. 552-64.
  
  .

Estonia

• In 2010 approximately 9,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 77,000; economic burden of new and prior fractures € 30 million (in 2010); by 2025 burden will increase by 18 % to € 35 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Finland

• In 2010 approximately 36,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 300,000; economic burden of new and prior fractures € 383 million (in 2010); by 2025 burden will increase by 34 % to € 514 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

• The total number of hip fractures increased by 70% within a 10-year period (1992-2002) [6]Lonnroos, E., et al., Increased incidence of hip fractures. A population based-study in Finland. Bone, 2006. 39(3): p. 623-7.
  
  .

Georgia

• It is estimated that only 25% of patients with hip fracture are hospitalized [7]International Osteoporosis Foundation: Eastern European & Central Asian Regional Audit: Epidemiology, cost & burden of osteoporosis in 2010. 2010;
  
  See link.

Germany

• A lifetime prevalence of any fracture was found to be 45% for men and 31% for women within the age range of 25-74 years; and 42% for men and 40% for women within the age range of 65-74 years [8]Meisinger, C., et al., [Epidemiology of limb fractures]. Orthopade, 2002. 31(1): p. 92-9.
  
  .

Greece

• In 2010 approximately 86,000 new fragility fractures; number of people aged 50+ with osteoporosis, approximately 640,000; economic burden of new and prior fractures € 680 million (in 2010); by 2025 burden will increase by 20 % to € 814 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

• During 1977-1992 there was an average annual increase of 7.6% for hip fractures [9]Paspati, I., A. Galanos, and G.P. Lyritis, Hip fracture epidemiology in Greece during 1977-1992. Calcif Tissue Int, 1998. 62(6): p. 542-7.
  
  .

Hungary

• In 2010 approximately 102,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 550,000; economic burden of new and prior fractures € 197 million (in 2010); by 2025 burden will increase by 15 % to € 226 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Ireland

• In 2010 approximately 18,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 170,000; economic burden of new and prior fractures € 223 million (in 2010); by 2025 burden will increase by 44 % to € 320 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Latvia

• In 2010 approximately 14,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 130,000; economic burden of new and prior fractures € 38 million (in 2010); by 2025 burden will increase by 13 % to € 43 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Lithuania

• In 2010 approximately 15,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 180,000; economic burden of new and prior fractures € 47 million (in 2010); by 2025 burden will increase by 15 % to € 54 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Luxembourg

• In 2010 approximately 2,700 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 22,000; economic burden of new and prior fractures € 22 million (in 2010); by 2025 burden will increase by 41 % to € 31 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Malta

• In 2010 approximately 2,600 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 20,000; economic burden of new and prior fractures € 17 million (in 2010); by 2025 burden will increase by 40 % to € 24 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Netherlands

• In 2010 approximately 76,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 820,000; economic burden of new and prior fractures € 824 million (in 2010); by 2025 burden will increase by 30 % to € 1,069 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Poland

• In 2010 approximately 170,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 1,800,000; economic burden of new and prior fractures € 593 million (in 2010); by 2025 burden will increase by 27 % to € 753 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Portugal

• In 2010 approximately 52,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 590,000; economic burden of new and prior fractures € 577 million (in 2010); by 2025 burden will increase by 24 % to € 717 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Romania 

• The prevalence of postmenopausal osteoporosis is estimated at 11.5%, which means that one in three Romanian women would be osteoporotic or osteopenic after the age of 55 [7]International Osteoporosis Foundation: Eastern European & Central Asian Regional Audit: Epidemiology, cost & burden of osteoporosis in 2010. 2010;
  
  See link.

• In 2010 approximately 94,000 new fragility fractures each year; number of people aged 50+ with osteoporosis, approximately 1 million; economic burden of new and prior fractures € 129 million (in 2010); by 2025 burden will increase by 17 % to € 151 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Russia

• It is estimated that 14 million people (10% of the population) suffer from osteoporosis and 20 million have osteopenia – leaving 34 million people at high risk of fracture [7]International Osteoporosis Foundation: Eastern European & Central Asian Regional Audit: Epidemiology, cost & burden of osteoporosis in 2010. 2010;
  
  See link. 

• In some Russian cities, the lack of hospitalization and surgery following hip fracture lends itself to an extremely high fracture rate of up to 45-52% during the first year following fracture [7]International Osteoporosis Foundation: Eastern European & Central Asian Regional Audit: Epidemiology, cost & burden of osteoporosis in 2010. 2010;
  
  See link.

• Of those who survive hip fracture, only 9% return to their previous level of daily activities [7]International Osteoporosis Foundation: Eastern European & Central Asian Regional Audit: Epidemiology, cost & burden of osteoporosis in 2010. 2010;
  
  See link.

Slovakia

• In 2010 approximately 39,000 new fragility fractures; number of people aged 50+ with osteoporosis is approximately 230,000; economic burden of new and prior fractures € 107 million (in 2010); by 2025 burden will increase by 31 % to € 140 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Slovenia 

• From 1998 to 2005, the total number of hip fractures increased by 40% [7]International Osteoporosis Foundation: Eastern European & Central Asian Regional Audit: Epidemiology, cost & burden of osteoporosis in 2010. 2010;
  
  See link.

• In 2010 approximately 16,000 new fragility fractures each year; number of people aged 50+ with osteoporosis, approximately 110,000; economic burden of new and prior fractures € 56 million (in 2010); by 2025 burden will increase by 37 % to € 77 million [4]Svedbom, A., et al., Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos, 2013. 8: p. 137.
  
  .

Spain

• There was a 54% increase in new cases of hip fracture within a 14-year period (1998-2002). This increase occurred mainly in women (64%) compared to men (19%) [10]Hernandez, J.L., et al., Trend in hip fracture epidemiology over a 14-year period in a Spanish population. Osteoporos Int, 2006. 17(3): p. 464-70.
  
  .

Sweden 

• The probability of sustaining an osteoporosis hip fracture at the age of 50 years is 23% in women and 11% in men. The risk of sustaining a clinical vertebral fracture is 15% in women and 8% in men. For any common osteoporotic fracture, the remaining lifetime risk is 46% in women and 22% in men [11]Kanis, J.A., et al., Long-term risk of osteoporotic fracture in Malmo. Osteoporos Int, 2000. 11(8): p. 669-74.
  
  .

• Hip fractures account for nearly as many hospital days as acute myocardial infarction and for more than prostate and breast cancers combined [12]Johnell, O., et al., The burden of hospitalised fractures in Sweden. Osteoporos Int, 2005. 16(2): p. 222-8.
  
  .

• Hip fractures cause nearly the same amount of deaths as breast cancer [13]Kanis, J.A., et al., The components of excess mortality after hip fracture. Bone, 2003. 32(5): p. 468-73.
  
  .

• Osteoporotic fractures in men account for more hospital bed days than those due to prostate cancer [14]Kanis, J.A., et al., Epidemiology of osteoporosis and fracture in men. Calcif Tissue Int, 2004. 75(2): p. 90-9.
  
  .

Switzerland 

• Between 2000-2020, osteoporosis hip, vertebral and wrist fracture are predicted to rise by 33%, 27% and 19%, respectively, if current prevention and treatment patterns are maintained [15]Schwenkglenks, M., et al., A model of osteoporosis impact in Switzerland 2000-2020. Osteoporos Int, 2005. 16(6): p. 659-71.
  
  .

• The annual costs of hospitalizations (in terms of duration of stay) for osteoporosis fractures were greater than those for myocardial infarction, stroke and breast cancer, and only slightly lower than for chronic obstructive pulmonary disease. For women, the costs associated with osteoporosis were higher than for all these diseases [16]Lippuner, K., et al., Incidence and direct medical costs of hospitalizations due to osteoporotic fractures in Switzerland. Osteoporos Int, 1997. 7(5): p. 414-25.
  
  .

• In 2000, hip fractures accounted for approximately half the direct medical hospitalization costs of patients with osteoporosis and/or related fractures. Among other common diseases in women and men, osteoporosis ranked number 1 in women and number 2 (behind COPD) in men [17]Lippuner, K., M. Golder, and R. Greiner, Epidemiology and direct medical costs of osteoporotic fractures in men and women in Switzerland. Osteoporos Int, 2005. 16 Suppl 2: p. S8-S17.
   
  
  .

• In 2010, it was estimated that about 74,000 new fragility fractures occurred, comprising 14,000 hip fractures, 11,000 vertebral fractures, 13,000 forearm fractures and 36,000 other fractures. The consequential economic burden of incident and previous fragility fractures was estimated at just over CHF 2 billion with incident fractures representing 76 % of this cost, long-term fracture care 21 % and pharmacological prevention 3 % [18]Svedbom, A., et al., Epidemiology and economic burden of osteoporosis in Switzerland. Arch Osteoporos, 2014. 9: p. 187.
  
  .

Ukraine 

• The estimated number of postmenopausal women with osteoporosis risk and osteopenia is 7 million (28% of the total number of women). A recent study reports that most of the Ukrainian population has vitamin D insufficiency or deficiency [7]International Osteoporosis Foundation: Eastern European & Central Asian Regional Audit: Epidemiology, cost & burden of osteoporosis in 2010. 2010;
  
  See link.

UK

• 1 in 2 women and 1 in 5 men will suffer a fracture after the age of 50 [19]van Staa, T.P., et al., Epidemiology of fractures in England and Wales. Bone, 2001. 29(6): p. 517-22.
  
  .