Members of IOF’s Committee of Scientific Advisors (CSA) are invited to join working groups based on their areas of expertise in order to formulate global policy, scientific guidance, reviews or IOF positions on important topics in the field. 

2020 was a productive year with 13  impactful papers published by IOF Working Groups or by IOF experts in collaboration with other societies in specific areas of expertise. Two more papers are in the pipeline for imminent publication. 

In case you missed our notifications throughout the year, here’s another opportunity to view and share IOF’s key papers of 2020:

• Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures. Kanis et al., Osteoporos Int 2020  
   
• Harmonization of commercial assays for PINP; the way forward. Vasikaran et al., Osteoporos Int 2020 
   
• Perspectives on the non-invasive evaluation of femoral strength in the assessment of hip fracture risk. Bouxsein et al., Osteoporos Int 2020 
   
• Short review: Diagnosis and management of bone fragility in diabetes: an emerging challenge. Ferrari et al., Journal of Diabetes Management and Metabolism 2020
   
• Fragility fractures in Europe: Burden, management and opportunities. Borgström et al., Arch Osteoporos 2020 
   
• A patient-level key performance indicator set to measure the effectiveness of fracture liaison services and guide quality improvement: a position paper of the IOF CTF, NOF and FFN. Javaid MK et al.  Osteoporos Int 2020
   
• European Biological Variation Study (EuBIVAS): Within- and between-subject biological variation estimates of β-isomerized C-terminal telopeptides of type I collagen (β-CTX), N-terminal propeptide of type I collagen (PINP), osteocalcin, intact Fibroblast growth factor 23 and uncarboxylated-unphosphorylated Matrix-Gla Protein: a cooperation between the EFLM Working Group on Biological Variation and the International Osteoporosis Foundation-International Federation of Clinical Chemistry Committee on Bone Metabolism. Cavalier et al., Osteoporos Int 2020 
   
• Guidelines for assessment of bone densitometry and microarchitecture in vivo using high resolution peripheral quantitative computed tomography. Whittier D et al. Osteoporos Int 2020
   
• Premenopausal osteoporosis: a clinical narrative review by the European Calcified Tissue Society and the International Osteoporosis Foundation. Pepe et al. JCEM 2020
   
• A multicenter study to evaluate harmonization of assays for N-terminal propeptide of type I procollagen (PINP): a report from the IFCC-IOF Joint Committee for Bone Metabolism. Cavalier E et al., IFCC-IOF Joint Committee for Bone Metabolism (C-BM). Clin Chem Lab Med. 2019
   
• Bone densitometry worldwide: a global survey by the ISCD and IOF. Clynes et al., Osteoporos Int. 2020
   
• European consensus statement on the diagnosis and management of osteoporosis in chronic kidney disease stages G4 to G5D. Evenepoel et al., Nephrology Dialysis Transplantation 2020
   
• Bone Fragility in Patients Affected by Congenital Diseases non-Skeletal in Origin. Masi et al. Orphanet Journal of Rare Diseases (in press)  

"This substantial body of work demonstrates the enthusiasm, expertise, productivity and commitment of members of the IOF Committee of Scientific Advisors, and colleagues in collaborating societies, in our global mission to prevent osteoporotic fractures. We extend our sincere thanks to everyone who has made such wonderful contributions to the work of the Foundation in 2020, and we very much look forward to continuing to work with you in 2021.” 

Professor Nicholas Harvey, CSA Chair
Professor Serge Ferrari, CSA Vice-Chair
Dr Philippe Halbout, IOF CEO
Professor Cyrus Cooper, IOF President